Showing posts with label muscle atrophy. Show all posts
Showing posts with label muscle atrophy. Show all posts

Sunday, January 9, 2011

Nutrition in Alcoholic Myopathy Treatment

Role of Nutrition in Alcoholic Myopathy 


Upon reviewing the research on the treatments and the causes of alcoholic myopathy, there is an obvious relationship between malnutrition and alcoholic myopathy yet little can be found regarding specific nutritional recommendations in the treatment of chronic alcoholic myopathy for those interested in addressing this important factor.

As there is a need for more studies on this sparsely researched topic, it is difficult to predict what specific effects on alcoholic myopathy may be expected from nutritional interventions. However, to get this dysfunction in the first place, one must drink alcohol excessively; and since heavy or chronic drinking leads to malnutrition, it is wise to consider nutritional therapy regardless of whether it will have a definite effect on the myopathy itself. Nonetheless, in determining a nutritional approach it makes sense to first consider the known deficiencies associated with myopathy…

Protein, Amino Acids in Alcoholic Myopathy Treatment


Since protein deficiency has been directly linked to myopathy, it is a good place to start. A nutritionist or health coach may be able to guide you in evaluating your protein intake to ensure you are getting the proper support of that key macronutrient involved in muscle health. While protein deficiency might have been a contributing factor to the myopathy, adequate protein intake is certainly necessary in the recovery from muscle atrophy.

Amino acids are the building blocks of protein, which is synthesized to build muscle. Some suggest that supplementing with amino acids may help accelerate the repair of muscle damage in myopathy.

Alcohol use disrupts the production of growth hormone, which also plays a major role in muscle development. Research suggests that decreased levels of growth hormone may also contribute to the myopathy of skeletal muscles, as with alcoholic myopathy. Certain amino acids stimulate the pituitary gland to produce and release growth hormone.

Prime™ Ultra Secretagogue is an excellent amino acids supplement recommended by many doctors to naturally and safely stimulate the body’s natural production of human growth hormone. It helps build protein to build lean muscle, in addition to offering a multitude of other health benefits. Be sure to scroll down when you check out the 
Prime™ Ultra Secretagogue page to learn more about the research, ingredients and benefits.

Antioxidants in Alcoholic Myopathy Treatment


There is evidence that suggests free radical damage in the pathogenesis of alcoholic myopathy. Free radicals are unpaired electrons, aka reactive oxygen species, which cause a chain reaction of damage of cells as they attempt to steal their missing electron from any nearby source. Antioxidants are able to replenish the unpaired electrons thus ending the cycle of damage. However, without sufficient antioxidants to combat the abundance of free radicals, the damaging process continues - and can affect any area of the body, including muscle tissue. Free radicals are caused by many factors including environmental toxins, alcohol, smoking, and physical and emotional stress to name a few.

Active and recovering alcoholics arguably have even more oxidative stress (free radicals) than the average person, and thus would benefit from antioxidant supplementation regardless of the potential benefit in the treatment of myopathy. Specific antioxidants called OPCs are awesome free radical fighters that also are known to help maintain normal muscle and nerve function – OPCs are potentially beneficial not only for myopathies but neuropathies as well; and some research suggests peripheral neuropathy may co-occur with alcoholic myopathy in 72% of cases!).

We also know that alcohol promotes inflammation in the body. Regardless of the type of myopathy, an effective antioxidant can address any inflammatory issues likely present in the recovering alcoholic (and definitely present in the active alcoholic!). Certain OPCs can act as a natural anti-inflammatory agent and are also known for a multitude of other health benefits.  Read more about the amazing benefits and science behind a highly absorbable and powerful OPC supplement ideal for recovering alcoholics.

Calcium and Alcoholic Myopathy Treatment


Research suggests chronic hypocalcemia (deficiency in calcium) may contribute to the increase in muscle damage in alcoholic myopathy. Everyone knows calcium is important in bone health, but it is also crucial in muscle function. Calcium is the most abundant mineral in the body, crucial to many health functions. All muscle fibers use calcium. Alcohol impairs the absorption of calcium!

Some other factors affecting your calcium levels…
Myth: “I drink milk, so I get plenty of calcium”. Fact: the calcium in most dairy products we consume is not bioavailable (we don’t absorb it!). You are better off skipping the pro-inflammatory dairy products, and increasing your green vegetables which have calcium that you will actually absorb.

Smokers – studies have shown that smoking interferes with efficient calcium absorbtion. Soda drinking (regardless if caffeinated or not, diet or regular) depletes calcium. Coffee and caffeine deplete calcium.
Also, those deficient in vitamin D are at risk for calcium deficiency as well because vitamin D is necessary for absorption of calcium… and many myopathy sufferers have been found to be deficient in vitamin D!

There are a lot of poor calcium supplements on the shelves. Many contain the wrong form, wrong amounts, and/or not the correct additional ingredients necessary for calcium absorption (ie vitamin D3 and magnesium) in the proper amounts. Individuals with alcoholism in particular have done damage to their digestive systems, so it is imperative to take the most absorbable form of a high quality calcium supplement.  Get more information on the best calcium supplement we have found (see label).

Vitamin D in Alcoholic Myopathy Treatment


Research has concluded that low vitamin D levels are related to muscle fiber atrophy, and vitamin D deficiency itself may induce myopathy. Low vitamin D levels are frequent in alcoholics. Studies show that vitamin D stimulates growth of muscle fibers. Regardless of whether the vitamin D deficiency caused the myopathy, vitamin D is helpful in recovery from the muscle atrophy. Experts estimate that most of the population is deficient in vitamin D. If in doubt, ask your physician for a blood test to evaluate your 25-hydroxy vitamin D levels; levels should be above 50 ng/ml (125 nmol/L) year-round. Read more about the research, benefits, and FAQ on a high quality vitamin D supplement.

In conclusion, hopefully more will be revealed in the future on this topic of nutritional supplementation in the treatment of alcoholic myopathy sufferers. In the meantime, as individuals seek to integrate a nutritional approach to treatment of alcoholic myopathy, a few important supplements to consider include: Prime™ Ultra Secretagogue, OPC-3, Calcium Complete, and Vitamin D.

Friday, August 13, 2010

Alcoholic Myopathy

What Is Alcoholic Myopathy?


Type 2 muscle atrophy
Myopathy means muscular disease, and generally refers to a disorder in which muscle weakness develops due to some malfunction of the actual muscle fibers. In addition to muscle weakness, symptoms of myopathy may also include muscle cramps or spasm and muscle stiffness. While some recovering alcoholics may have never heard of alcoholic myopathy, it more common than one may think. Some research indicates that about one third of heavy long-term drinkers, aka alcoholics, develop skeletal myopathy.

The history of the myopathy related to alcoholics can be traced back to the 19th century, when there were reports of “alcoholic paralysis” which is believed to be referencing the muscle disease known today as alcoholic myopathy. Most specifically, in the mid 1800's, Magnus Huss wrote Alcoholismus Chronicus in which he reported identifying muscular weakness in patients resulting from alcohol use. Later, in the 1950’s and 1960’s, researchers went on to discover two distinct types of alcoholic myopathy: acute alcoholic myopathy and chronic alcoholic myopathy.

Acute Alcoholic Myopathy


Acute alcoholic myopathy develops suddenly, during an episode of binge drinking or immediately following during withdrawal. Acute alcoholic myopathy is also called “alcoholic rhabdomyolysis”. It can come on rapidly over the course of a few hours and can advance over a few days before receding over the week, given the individual abstains from alcohol. Acute myopathy can present mild to severe symptoms as a result of myonecrosis, the breakdown of muscle tissue.

Symptoms of acute alcoholic myopathy may include muscle pain and swelling in addition to the classic weakness. Often the acute symptoms are reported upon awakening from an alcoholic stupor; they may also accompany withdrawal symptoms and delirium tremens. Tests have revealed that acute alcoholic myopathy affects type I muscle fibers, which can heal rapidly; however type II muscle fibers are involved in chronic alcoholic myopathy.

Typically, full recovery from acute alcoholic myopathy occurs in a matter of days or weeks; however, in extreme cases when kidney failure or hyperkalemia (abnormal potassium level in the blood) occur, the alcoholic may actually die during the episode of acute myopathy. Otherwise, research has shown it takes about 7 to 10 days for the serum creatine kinase levels (reflecting the health of the muscle) to return to normal range.

Chronic Alcoholic Myopathy


In contrast to the acute form, chronic alcoholic myopathy develops much more gradually and lasts far longer. While the acute version may include muscle pain, chronic alcoholic myopathy is usually painless. The absence of pain and gradual onset may explain why it is frequently overlooked and not diagnosed until the symptoms have been present for several years. The recovery time for chronic myopathy is slower and can take many months (again, given the patient abstains from alcohol use).

Chronic alcoholic myopathy is associated with long term alcohol abuse (i.e. years of daily alcoholic drinking). It evolves slowly, over weeks or months as opposed to its acute counterpart which can develop in a matter of hours or days. The main symptom of chronic alcoholic myopathy is muscle weakness and atrophy. It affects proximal muscles, and type 2 muscle fibers. Interestingly, long term corticosteroid use can lead to similar type 2 atrophy as well, a.k.a. “steroid myopathy”.

Other disorders which may co-occur with chronic alcoholic myopathy include peripheral neuropathy. While with myopathy the primary dysfunction exists within the muscle itself, with neuropathy the dysfunction pertains to the nervous system (i.e. nerves or brain). Some research suggests peripheral neuropathy is associated in 72% of cases.

What Causes Alcoholic Myopathy?


Studies have linked the damaging effects of toxic ethanol (drinking alcohol) to alcoholic myopathy. The injurious effects of acetaldehyde as well as ethanol have been directly linked with alcoholic myopathy. Interestingly, acetaldehyde is also a prime suspect in the cause of hangover symptoms.

On a molecular level, the exact mechanism behind how alcohol produces myopathy remains elusive. Various studies and theories have been presented. Impaired IGF-1 signaling, protein deficiency, vitamin and mineral deficiencies, and other factors have been considered. For example, some research results suggested that protein deficiency and ethanol contributed to muscle atrophy in rats given alcohol and those underfed protein had the greatest myopathic effect.

Research suggests that ethanol consumption and malnutrition can lead to alcoholic myopathy, and most likely it is a combination of both working synergistically to produce the myopathy. The long term effect of alcohol abuse itself tends to cause malnutrition, so long term daily drinkers set themselves up to be malnourished, and thus also more vulnerable to the possibility of chronic myopathy.

Treatment for Alcoholic Myopathy


If the root of alcoholic myopathy is ethanol consumption and malnutrition, obviously abstinence from alcohol and proper nutrition are the best place to start. Alcoholic myopathy generally begins to reverse once the individual achieves complete abstinence from alcohol. So if you are a newly recovering alcoholic experiencing chronic myopathy, it is important to know the recovery typically takes many weeks or several months.

As the recovery time frame varies, proactive steps such as nutritional interventions may help to accelerate the recovery process. Physical therapy and acupuncture are sometimes utilized as well to target the effects of chronic myopathy.

Here is a quick response from a neurosurgeon who answered an online inquiry from an individual who asked: is there any treatment for alcoholic myopathy? The MD answered…
“Alcoholic myopathy is a tough condition:
1. stop alcohol
2. correct liver dysfunction
3. get a muscle biopsy to be sure the dx is correct.
4. See a nutritionist
5. Be followed carefully by a darned good neurologist
6. slow rehab with careful attention to enzyme changes.”

There seems to be little information on specific nutritional information to benefit individuals suffering from alcoholic myopathy. After further research, a follow up article is posted with more detailed suggestions for a proactive holistic approach to potentially accelerating recovery from alcoholic myopathy - check out article on "Nutrition in Alcoholic Myopathy Treatment".